Persistent agent frameworks that run locally — on your Mac, VPS, or GPU cloud.

Self-improving agent by Nous Research
A self-improving AI agent by Nous Research with a built-in learning loop, persistent memory, autonomous skill creation, and 15+ messaging integrations.
Self-hosted AI assistant gateway
A self-hosted AI assistant gateway that connects 32+ messaging platforms to AI coding agents. Runs on your own hardware with no hosted service dependency.
If you want help navigating software rather than a persistent runtime, an on-screen assistant serves a different need. Our Guidy AI review explains the task fit, pricing, and privacy questions before you try it.